alcohol acetominophen glutathione napqi cytochrome p450 Interaction with Ethanol – Metabolism GSH reduces NAPQI, the metabolite

GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Xia & He Publishing Translational biomarkers of acetaminophen induced acute liver injury Archives of Toxicology Springer Nature Link A Review of Bioinformatics Tools to Understand Acetaminophen Alcohol Interaction added a new Figure depicting the pathways of the metabolism of acetaminophen (paracetamol) to the Ethanol Metabolism page: https: themedicalbiochemistrypage.org ethanol metabolism.php NAPQI Alchetron, The Free Social Encyclopedia

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